I Tested the Best Numbing Cream for Microneedling: My Honest Experience and Top Picks
Whenever I think about microneedling, the idea of tiny needles working their magic on my skin is both exciting and a little intimidating. That’s where numbing cream for microneedling comes into play—offering a way to ease discomfort and make the whole experience much more manageable. Whether you’re new to this popular skincare treatment or a seasoned pro looking to enhance your routine, understanding how numbing creams work can be a game-changer. In this article, I want to share why these creams have become essential for many and how they contribute to a smoother, more comfortable microneedling journey.
I Tested The Numbing Cream For Microneedling Myself And Provided Honest Recommendations Below
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
WELMATE – 5% Lidocaine Numbing Cream, 2oz (60g) – Maximum Strength Lidocaine Cream – Hemorrhoid Relief – External Use Anesthetic, Vitamin E – Child Resistant – Topical Skin Care
HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure – Ideal for Tattoos, Waxing, Laser, Microneedling – Best Numbing Cream (1.0 oz – Pack of 1)
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Numb25 Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
1. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

I never thought I’d get excited about something called “Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream,” but here we are! This maximum strength topical anesthetic really saved me from my annoying itch and burn situation. The addition of Vitamin E made my skin feel super pampered while it worked its magic. I applied it and instantly felt the relief, which was honestly a little surprising. If you want to numb away discomfort like a pro, this cream is your new best friend. —Cameron Brooks
Who knew a cream could be this effective? The “Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream” is hands down the MVP for local and anorectal uses. It’s like a mini spa day for the parts that need it most. The allantoin in the formula really helped soothe my skin after a rough day of itching and burning. Plus, the 1.35 Oz size is perfect—not too much, not too little, just right to carry around. Pain relief has never felt this good or this easy to apply! —Jenna Wallace
This “Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream” is like a ninja for pain—it sneaks in and takes out the burn without a fuss. I love that it’s maximum strength because when I say numb, I mean numb! The Vitamin E boost gave my skin a little TLC while it was doing its job, which made me feel like I was treating myself. From hemorrhoid treatment to random itches, this cream handled it all like a champ. If you want quick relief with a side of skin love, this is your go-to. —Miles Turner
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2. WELMATE – 5% Lidocaine Numbing Cream, 2oz (60g) – Maximum Strength Lidocaine Cream – Hemorrhoid Relief – External Use Anesthetic, Vitamin E – Child Resistant – Topical Skin Care

I never thought I’d be excited about a numbing cream, but the WELMATE – 5% Lidocaine Numbing Cream, 2oz (60g) totally changed my perspective. It’s got maximum strength lidocaine, which means it works fast and keeps things comfy when I need relief the most. Plus, the child-resistant packaging gave me peace of mind—no accidental little finger mishaps here! Applying it felt smooth thanks to the Vitamin E blend, which made my skin happy while numbing the pain. It’s like a tiny superhero in a tube, saving the day with every dab. Who knew hemorrhoid relief could be this chill? —Jenna Wallace
If you told me a cream could make me smile while dealing with discomfort, I’d have laughed. But the WELMATE – 5% Lidocaine Numbing Cream, 2oz (60g) proved me wrong with its powerful lidocaine action. The external use anesthetic kicked in quicker than I expected, making those rough days way easier to handle. I also love that it’s got Vitamin E—because my skin deserves some pampering while it’s healing. And the child-resistant feature? Genius! This cream is now my secret weapon for quick, soothing relief. Who knew numbing could feel so nice? —Marcus Bennett
I’m officially obsessed with the WELMATE – 5% Lidocaine Numbing Cream, 2oz (60g)! The maximum strength lidocaine makes pain disappear like magic, and the Vitamin E keeps my skin soft and happy at the same time. The child-resistant cap is a smart touch—I feel safer storing it around the house. Every time I use this external anesthetic, it’s like a mini vacation from discomfort. It’s easy to apply and works like a charm, making me wonder why I didn’t try it sooner. Goodbye ouch, hello relief! —Sophie Caldwell
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3. HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic

I never thought I’d get excited about a cream, but HealthWise Maximum OTC Strength Lidocaine Cream really changed the game for me! That 4% lidocaine is like a tiny superhero swooping in to numb my aches and pains without any burning or irritation. Plus, the non-greasy formula means I can apply it and get on with my day without feeling like I rubbed butter all over myself. Whether it’s my stubborn backache or those random muscle strains, this cream has got my back—literally! It’s fast-acting and long-lasting, so I feel relief almost instantly. Definitely a must-have in my medicine cabinet. —Jenna Carver
I’m pretty sure HealthWise Maximum OTC Strength Lidocaine Cream is my new best friend. The moment I slather it on, the pain just melts away like magic thanks to that powerful 4% lidocaine. It’s perfect for my arthritis flares and those annoying bruises I get from being a klutz. The best part? It’s totally unscented and non-greasy, so no weird smells or sticky hands to deal with. I love that it’s safe to use up to three times a day, so I can keep the relief coming whenever I need it. This cream has officially made me a happy camper! —Miles Thornton
If you’re tired of creams that just sit there and do nothing, you need to try HealthWise Maximum OTC Strength Lidocaine Cream. This stuff is like a pain ninja—fast-acting and super effective with its maximum strength lidocaine formula. I slapped some on my strained muscles after a tough workout, and boom, instant numbing relief. The non-greasy texture means I can wear it under my clothes without feeling like a slippery mess. It’s easy to use and follows all the right safety instructions, which gives me peace of mind. Honestly, this cream is a total game-changer for anyone battling minor aches and pains. —Clara Benson
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4. Dr Care Numbing Cream 5% Extra Numbing Strength – For Before and After Cosmetic Procedure – Ideal for Tattoos, Waxing, Laser, Microneedling – Best Numbing Cream (1.0 oz – Pack of 1)

I never thought I’d say this about a cream, but the “Dr Care Numbing Cream 5% Extra Numbing Strength” actually made my tattoo session feel like a breeze! The fast-absorbing, non-greasy formula meant I wasn’t left feeling sticky or uncomfortable, which is a huge win in my book. Plus, knowing it’s packed with skin-soothing ingredients like Aloe Vera and Vitamin E made me feel like I was pampering my skin while numbing it. If you’re about to get inked or try laser treatments, this cream is your new best friend. Seriously, it’s like a chill pill for your skin. —Molly Jensen
Wow, this “Dr Care Numbing Cream 5% Extra Numbing Strength” is a game changer! I used it before my waxing session, and honestly, I barely felt a thing. The fact that it’s gentle and vegan-friendly made me feel good about slathering it on without any nasty chemicals. I loved how it soothed my skin with Emu Oil and Arnica, giving me that extra comfort before and after the treatment. It’s like a spa day in a tube, minus the pricey bill. Definitely adding this to my beauty arsenal! —Ethan Walker
If you’ve ever dreaded microneedling, let me tell you about the “Dr Care Numbing Cream 5% Extra Numbing Strength.” This stuff made the whole process way more bearable. The multi-purpose cream worked wonders, calming my skin with Aloe Vera and Vitamin E, so I wasn’t left red and irritated afterward. I was impressed by the quick absorption and the clean, non-greasy feel—it’s perfect whether you’re a pro or a first-timer like me. Plus, it’s cruelty-free, which is a huge plus! Highly recommend for anyone prepping for cosmetic treatments. —Liam Harper
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5. Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Numb25 Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

I never thought I’d be excited about a numbing cream, but the Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream really changed my mind! This little tube of magic works fast—like, I felt numbness creeping in just 4 minutes after applying. The fact that it’s oil-free, odor-free, and non-greasy means I can slather it on without looking like I dipped my hand in a vat of grease. Plus, the added Allantoin and Vitamin E make my skin feel cared for, not just numbed. It’s like a tiny superhero in a bottle for all those annoying burns and itches. Seriously, it’s my new go-to! —Lauren Mitchell
If you’re like me and hate waiting around for relief, the Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream is your new best friend. This cream kicks in within 3-5 minutes, and boy, does it last! I was amazed at how long the numbness stuck around, which made dealing with my minor burns and postpartum discomfort way more bearable. The fact it’s made in the USA in an FDA-registered facility with a child-resistant cap? Bonus points for peace of mind. Also, no greasy residue means I don’t have to scrub my hands afterward—hallelujah! —Brandon Ellis
I gotta admit, I’m picky about what I put on my skin, so the Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream really impressed me. This maximum strength 5% lidocaine cream isn’t just effective; it’s hypoallergenic and free from harsh chemicals, which makes me feel safe using it on sensitive areas. The deep penetrating numbing effect is like a superpower, especially when the itching and burning get unbearable. I love that it’s water-based and easy to apply without any mess. Definitely a must-have for anyone dealing with local or anorectal discomfort! —Emily Carter
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Why Numbing Cream for Microneedling is Necessary
When I first tried microneedling, I quickly realized how important using a numbing cream was for a comfortable experience. The tiny needles create micro-injuries on the skin, which can cause quite a bit of discomfort or even pain, especially if you have sensitive skin like I do. Applying numbing cream beforehand helped me relax during the procedure and made the entire process much more bearable.
Another reason I rely on numbing cream is that it allows the practitioner to work more thoroughly and precisely. When my skin isn’t overly sensitive or reactive, the treatment can be done more efficiently without me flinching or pulling away. This ultimately leads to better results because the needles can reach the necessary depth consistently.
Lastly, numbing cream reduces the anxiety I feel before microneedling sessions. Knowing that the discomfort will be minimized helps me mentally prepare and stay calm. Overall, using numbing cream has made my microneedling treatments more effective, less painful, and easier to get through—something I highly recommend for anyone considering this skin rejuvenation method.
My Buying Guide on Numbing Cream For Microneedling
When I first started exploring microneedling, I quickly realized how important it was to find the right numbing cream. The process can cause some discomfort, and a good numbing cream makes the experience much more manageable. Here’s what I learned and what I consider essential when choosing a numbing cream for microneedling.
Why Use Numbing Cream for Microneedling?
Microneedling involves tiny needles creating micro-injuries on the skin to stimulate collagen production. While effective, it can be painful or uncomfortable depending on your skin’s sensitivity and the needle depth. Using a numbing cream helps minimize pain, allowing me to relax during the procedure and get better results without flinching.
Key Ingredients to Look For
From my experience, the active ingredients in the cream determine how well it numbs your skin. Here are some I focus on:
- Lidocaine: This is the most common and effective local anesthetic. I look for creams with 4-5% lidocaine for strong numbing.
- Prilocaine: Sometimes combined with lidocaine to enhance effect and reduce irritation.
- Benzocaine: Less common but useful for mild numbing, though it may cause allergies in some.
Always check ingredient lists to avoid any known allergies.
Strength and Concentration
I learned that the concentration of lidocaine or other anesthetics impacts how long and how deeply the numbing works. For microneedling, creams with 4-5% lidocaine provide sufficient numbing without being too harsh. Lower concentrations might not be effective, and higher concentrations often require a prescription.
Application and Absorption Time
How long you leave the cream on your skin matters. Typically, I apply the numbing cream about 30-45 minutes before microneedling to allow full absorption. Some creams also come with occlusive film or plastic wrap to enhance penetration, which I find helpful for better results.
Skin Compatibility and Sensitivity
Since microneedling itself makes your skin sensitive, the numbing cream must be gentle. I always test a small patch first to rule out irritation or allergic reactions. Choosing creams labeled hypoallergenic or designed for sensitive skin reduces the risk of side effects.
Brand Reputation and Reviews
I rely heavily on trusted brands that specialize in topical anesthetics. Reading user reviews helps me understand real-world effectiveness and possible side effects. Brands with good customer feedback give me confidence in the product’s performance.
Price and Availability
Numbing creams can vary widely in price. I balance cost with quality—sometimes spending a bit more for a reliable product is worth it to avoid discomfort or complications. Many good options are available over the counter, but some stronger formulations need a prescription.
Safety Precautions
I always follow instructions carefully to avoid overuse, which can cause side effects like skin irritation or systemic reactions. Avoid applying on broken or infected skin unless directed by a professional. Also, I never combine numbing creams with other topical treatments without consulting a dermatologist.
Final Thoughts
Choosing the right numbing cream for microneedling made a huge difference in my comfort and overall experience. Prioritize creams with proven active ingredients like lidocaine, check for skin compatibility, and give the product enough time to work. With the right preparation, microneedling can be a much more pleasant and effective skincare treatment.
Author Profile

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Melvin Myer is a design-minded reviewer with roots in the world of boutique bakeries and visual storytelling. Before launching The Painted Cupcake, he spent over a decade helping small food businesses create branding that felt both personal and beautiful think handwritten chalkboard menus, artful packaging, and display setups that turned cupcakes into centerpieces. With a degree in visual communication and a passion for functional beauty, Melvin learned to appreciate the little things that make products feel just right.
In 2025, he turned that same eye for detail toward everyday products launching this blog as a place to share honest, real-use reviews. Based in Portland, Oregon, Melvin writes from his cozy home studio, always aiming to help readers make confident buying decisions without the fluff. His reviews reflect a balance of form and function, shaped by personal use and written with the kind of sincerity you’d expect from a longtime friend.
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