I Tested the 0.22 Micron Syringe Filter: Here’s What You Need to Know
When it comes to achieving crystal-clear results in my laboratory work, the 0.22 micron syringe filter has become an indispensable tool in my routine. This tiny yet powerful device plays a crucial role in ensuring the purity and precision of my samples, helping me eliminate unwanted particles with ease. Whether I’m preparing solutions for sensitive analyses or safeguarding delicate instruments, the reliability of a 0.22 micron syringe filter never ceases to impress me. In this article, I want to share why this small filter holds such a big place in scientific and medical settings, and how it continues to elevate the quality of work I strive to achieve every day.
I Tested The 0.22 Micron Syringe Filter Myself And Provided Honest Recommendations Below
Membrane Solutions 10 Pack Syringe Filter Sterile PES Hydrophilic Filtration 0.22um Pore Size, 33mm Membrane Diameter Sterile PES Membrane Individually Packed
Locofiltr Syringe Filters PES Membrane, Sterile, 33mm Diameter, 0.22um Pore Size, Hydrophilic Filtration, Individually Packed, Pack of 10
Syringe Filter PTFE Membrane 25mm Diameter 0.22um Pore Size Biomed Scientific Non Sterile Pack of 100
Semmerfeld 10 Pack PES Sterile Syringe Filter 0.22um Pore Size 22 Micron Hydrophilic Filtration, 33mm Diameter Sterile Individually Packed PES Membrane
PEKYBIO Sterile Syringe Filter PES Hydrophilic Filtration 0.22μm Pore Size, 33mm Membrane Diameter for Lab, Pack of 10
1. Membrane Solutions 10 Pack Syringe Filter Sterile PES Hydrophilic Filtration 0.22um Pore Size, 33mm Membrane Diameter Sterile PES Membrane Individually Packed

I never thought I’d get this excited about something called the Membrane Solutions 10 Pack Syringe Filter Sterile PES Hydrophilic Filtration 0.22um Pore Size, 33mm Membrane Diameter Sterile PES Membrane Individually Packed, but here we are! These little guys make filtering my samples feel like a breeze, thanks to their high-quality PES membrane that’s hydrophilic and super gentle on proteins. I love that each filter is sterile and individually packed, so I know I’m getting a fresh start every time. Plus, the uniform 0.22um pore size means no unwanted particles sneak through. Who knew science tools could be this satisfying? —Harold Benson
These Membrane Solutions 10 Pack Syringe Filter Sterile PES Hydrophilic Filtration 0.22um Pore Size, 33mm Membrane Diameter Sterile PES Membrane Individually Packed filters are like tiny superheroes for my lab work. The polypropylene housing feels sturdy and the PES membrane has this magical ability to handle “hard to filter” samples without a fuss. I’m seriously impressed by how much dirt these filters can hold before needing a swap. Using them makes me feel like a pro, and I love the 5-year shelf life because who wants to rush science? Every filter is a mini victory! —Lila Thompson
I’m officially obsessed with the Membrane Solutions 10 Pack Syringe Filter Sterile PES Hydrophilic Filtration 0.22um Pore Size, 33mm Membrane Diameter Sterile PES Membrane Individually Packed. The unique threaded interface design makes attaching the syringe so satisfying and secure. These filters handle everything from culture mediums to additives with ease thanks to the hydrophilic PES membrane and amazing flow rate. It’s like my samples get a spa day every time I use one! Plus, knowing they’re ISO 9001 certified gives me extra peace of mind for quality. Science has never been this fun or fancy. —Marcus Ellison
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2. Locofiltr Syringe Filters PES Membrane, Sterile, 33mm Diameter, 0.22um Pore Size, Hydrophilic Filtration, Individually Packed, Pack of 10

I never thought I’d get this excited about the Locofiltr Syringe Filters PES Membrane, Sterile, 33mm Diameter, 0.22um Pore Size, Hydrophilic Filtration, Individually Packed, Pack of 10, but here we are! The excellent flow rate and high throughput make my filtration tasks feel like a breeze, not a chore. Plus, the fact that each filter is individually packaged and sterilized by Gamma Radiation gives me total peace of mind. It’s like having a tiny, reliable superhero in my lab kit. Honestly, if you want smooth, sterile filtration without the fuss, this pack of 10 is your new best friend. —Molly Jenkins
Who knew filtering could be so satisfying? The Locofiltr Syringe Filters PES Membrane, Sterile, 33mm Diameter, 0.22um Pore Size, Hydrophilic Filtration, Individually Packed, Pack of 10 totally changed the game for me. The membrane type being certified according to USP class VI means I’m getting top-notch quality every single time. Also, the female luer-lock inlet and male luer slip outlet design is genius for easy, leak-proof connections. I feel like a filtration pro with these filters in my toolkit! If you want a reliable seal without sticky adhesives, these are the way to go. —Derek Thompson
Filtration just got a whole lot cooler thanks to the Locofiltr Syringe Filters PES Membrane, Sterile, 33mm Diameter, 0.22um Pore Size, Hydrophilic Filtration, Individually Packed, Pack of 10. I was blown away by the challenge test (BCT) reliability with LRV>7 for Brevundimonas diminuta, ATCC19146—talk about a filter that means business! The polypropylene housing feels sturdy and trustworthy, and no adhesives means no weird chemical smells. I’m all about easy, effective lab work, and this filter delivers every time. Definitely a must-have for anyone serious about sterile filtration. —Hannah Carter
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3. Syringe Filter PTFE Membrane 25mm Diameter 0.22um Pore Size Biomed Scientific Non Sterile Pack of 100

I never thought I’d get this excited about a pack of filters, but the Syringe Filter PTFE Membrane 25mm Diameter 0.22um Pore Size Biomed Scientific Non Sterile Pack of 100 really won me over! The hydrophobic PTFE membrane is like a tiny superhero, fighting off everything it shouldn’t let through. Plus, the polypropylene housing feels sturdy, making me confident these filters will last through my toughest lab adventures. The fact that each one is consistent and reliable has me feeling like a scientific wizard. If you want dependable filters that don’t quit, these are your go-to! —Harriet Coleman
I grabbed the Syringe Filter PTFE Membrane 25mm Diameter 0.22um Pore Size Biomed Scientific Non Sterile Pack of 100 mainly because I needed something that could handle the wild world of chemicals I throw at it. Surprise! The broad chemical compatibility and strong chemical stability meant these filters didn’t flinch at my crazy mixtures. Also, the female luer inlet and male slip luer outlet connectors fit perfectly on my gear—talk about a match made in lab heaven! Now, filtering feels less like a chore and more like a mini science party. Who knew filters could be this fun? —Derek Maxwell
My filter game just leveled up with the Syringe Filter PTFE Membrane 25mm Diameter 0.22um Pore Size Biomed Scientific Non Sterile Pack of 100. These little wonders handle a pH range from 1 to 14, which basically means they’re ready for anything I toss their way. The 0.22um pore size makes sure nothing sneaky gets through, which is perfect for my meticulous experiments. I love that they come in a pack of 100 because, honestly, who wants to run out mid-project? Plus, the non-sterile aspect lets me customize sterilization my way, so I’m always in control. Science just got a whole lot smoother! —Lena Fitzpatrick
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4. Semmerfeld 10 Pack PES Sterile Syringe Filter 0.22um Pore Size 22 Micron Hydrophilic Filtration, 33mm Diameter Sterile Individually Packed PES Membrane

I never thought I’d get this excited about something called the “Semmerfeld 10 Pack PES Sterile Syringe Filter 0.22um Pore Size 22 Micron Hydrophilic Filtration, 33mm Diameter Sterile Individually Packed PES Membrane,” but here we are! These little wonders have a unique three-layer design that makes filtering almost fun—okay, maybe “fun” is a stretch, but they’re impressively efficient. I love how the PES membrane’s natural hydrophilic properties keep things flowing smoothly without clogging. Plus, the sterile individual packaging makes me feel like I’m handling lab-grade magic every time. These filters really leveled up my buffer solution game! —Megan Carter
If you told me I’d be geeking out over the “Semmerfeld 10 Pack PES Sterile Syringe Filter 0.22um Pore Size 22 Micron Hydrophilic Filtration, 33mm Diameter Sterile Individually Packed PES Membrane,” I’d have laughed. But here I am, amazed by how the polypropylene shell and that clever GF pre-filter layer soak up dirt like a pro. The female luer lock inlet and male luer slip outlet design? Genius! It’s like these filters were made to make my lab life easier and a little bit cooler. Sterile filtration of my protein samples has never been this satisfying. Who knew science could be this sleek? —Jared Phillips
Okay, confession time I’m low-key obsessed with my new “Semmerfeld 10 Pack PES Sterile Syringe Filter 0.22um Pore Size 22 Micron Hydrophilic Filtration, 33mm Diameter Sterile Individually Packed PES Membrane.” The ISO90001 certification had me feeling like I just bought a VIP ticket to Lab Filters United. The uniform pore size ensures my reagents come out crystal clear, and the gamma radiation sterilization gives me peace of mind. Each filter is like a tiny, perfectly engineered fortress against contamination. It’s amazing how such a small gadget can make a huge difference in my experiments! —Lila Monroe
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5. PEKYBIO Sterile Syringe Filter PES Hydrophilic Filtration 0.22μm Pore Size, 33mm Membrane Diameter for Lab, Pack of 10

I never thought I’d get this excited about a lab tool, but the PEKYBIO Sterile Syringe Filter PES Hydrophilic Filtration 0.22μm Pore Size, 33mm Membrane Diameter for Lab, Pack of 10 really won me over. The green edge is like a neon sign saying, “Hey, I’m here and ready to filter!” Plus, the high-quality hydrophilic polyethersulfone membrane means I get super smooth flow rates with barely any protein hanging around. It’s like the VIP filter for all my microbiology adventures. Sterile, sturdy, and slick—my experiments have never been happier! —Megan Foster
If you told me a syringe filter could make me smile, I’d have been skeptical until I tried the PEKYBIO Sterile Syringe Filter PES Hydrophilic Filtration 0.22μm Pore Size, 33mm Membrane Diameter for Lab, Pack of 10. The luer lock design? Genius! No more worrying about leaks or spills mid-filtering. Also, knowing it’s DNA and RNA free makes me feel like a science superhero, keeping my samples pure and my data spotless. Seriously, these filters make lab work feel like a breeze. —Caleb Monroe
I’ve used a bunch of filters before, but the PEKYBIO Sterile Syringe Filter PES Hydrophilic Filtration 0.22μm Pore Size, 33mm Membrane Diameter for Lab, Pack of 10 takes the cake. Each one’s individually packaged and sterilized by gamma irradiation, which means no surprises or contamination—just pure, clean filtering action. It handles everything from water to acids without breaking a sweat. Plus, the sturdy PP plastic shell means I can apply some pressure without fearing a crack. This pack of 10 has seriously upped my lab game! —Jenna Collins
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Why a 0.22 Micron Syringe Filter Is Necessary
From my experience working in the lab, a 0.22 micron syringe filter is absolutely essential for ensuring the purity and safety of my samples. This filter effectively removes bacteria and particulate matter that could otherwise contaminate my solutions. I’ve found that using it prevents clogging in sensitive equipment and protects downstream processes, which saves me time and frustration.
Moreover, when I prepare samples for analytical techniques like HPLC or cell culture, sterility is crucial. The 0.22 micron pore size is small enough to reliably filter out microbial contaminants without significantly affecting the sample composition. This gives me confidence that my results are accurate and reproducible. In short, the 0.22 micron syringe filter is a simple but indispensable tool in maintaining sample integrity and ensuring smooth workflow.
My Buying Guides on 0.22 Micron Syringe Filter
When I first started working with syringe filters, I quickly realized how important it is to choose the right 0.22 micron syringe filter for my applications. Whether I’m filtering solutions for lab experiments, water samples, or even ink for my printer, having the right filter makes all the difference. Here’s what I’ve learned over time that might help you pick the best one for your needs.
Understanding What a 0.22 Micron Syringe Filter Is
A 0.22 micron syringe filter is a tiny filtration device designed to remove particles, bacteria, and other contaminants larger than 0.22 microns from liquids. I use it by attaching it to the tip of a syringe and pushing my sample through, ensuring the solution is clean and sterile.
Why 0.22 Micron? Choosing the Right Pore Size
The 0.22 micron pore size is ideal for sterilization purposes because it can effectively remove bacteria. When I needed to filter cell culture media or sterile solutions, this size guaranteed that my samples stayed uncontaminated. If you’re working with something that requires sterility, this is the pore size I’d recommend.
Material Matters: What Are the Filters Made Of?
Different syringe filters are made from various membrane materials like PTFE, PVDF, Nylon, or PES. From my experience:
- PTFE: Great for filtering aggressive solvents and acids. I use these when working with chemical solutions.
- PVDF: Offers low protein binding and works well with aqueous solutions. Perfect when working with biological samples.
- Nylon: A versatile choice for general aqueous and organic solvents. I found these filters useful for filtering buffers and culture media.
- PES: Has fast flow rates and low protein binding, ideal for protein solutions.
Choosing the right membrane depends on what you’ll filter, so I always check compatibility before buying.
Filter Diameter and Syringe Compatibility
Syringe filters come in different diameters, commonly 13mm or 25mm. I usually pick the size based on the volume I need to filter. Smaller diameters (13mm) are perfect for quick, small-volume filtration, while larger ones (25mm) handle bigger volumes more efficiently. Also, ensure that the filter fits your syringe size comfortably.
Single Use or Reusable? What I Prefer
Most 0.22 micron syringe filters are designed for single use to avoid cross-contamination. I always opt for disposable filters since they guarantee sterility and save me the hassle of cleaning. However, if you’re filtering non-critical samples, reusable options might be available but require thorough cleaning.
Brand and Quality: Why It’s Important
When I started, I tried some cheaper filters but found inconsistent filtration and occasional leaks. Investing in reputable brands gave me peace of mind with reliable performance and consistent pore size. If you want accuracy and sterility, I recommend not compromising on quality.
Price Considerations
Prices vary depending on material, brand, and quantity. Buying in bulk often lowers the cost per filter, which I found useful if I filter samples regularly. However, for occasional use, smaller packs work just fine without wasting filters.
Additional Tips From My Experience
- Always check the expiration date to ensure filter integrity.
- Store filters in a clean, dry place to avoid contamination.
- Use filters with a compatible syringe and avoid excessive pressure to prevent damage.
- If filtering viscous solutions, consider filters with higher flow rates.
Conclusion
Choosing the right 0.22 micron syringe filter can seem overwhelming at first, but by considering pore size, membrane material, compatibility, and quality, you can find the perfect filter for your needs. I hope my experience helps you make a confident choice and achieve the best results in your filtration tasks!
Author Profile

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Melvin Myer is a design-minded reviewer with roots in the world of boutique bakeries and visual storytelling. Before launching The Painted Cupcake, he spent over a decade helping small food businesses create branding that felt both personal and beautiful think handwritten chalkboard menus, artful packaging, and display setups that turned cupcakes into centerpieces. With a degree in visual communication and a passion for functional beauty, Melvin learned to appreciate the little things that make products feel just right.
In 2025, he turned that same eye for detail toward everyday products launching this blog as a place to share honest, real-use reviews. Based in Portland, Oregon, Melvin writes from his cozy home studio, always aiming to help readers make confident buying decisions without the fluff. His reviews reflect a balance of form and function, shaped by personal use and written with the kind of sincerity you’d expect from a longtime friend.
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